Why is haemophilia uncommon in human females?

ICSE Class 10 Biology PYQ · 2027 Specimen · Section B

6(iv)Written · 2027 · Section B · 2027 Specimen

Why is haemophilia uncommon in human females?

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Haemophilia is a sex linked recessive disorder carried on the X chromosome. A female has two X chromosomes, so she will suffer from the disease only if both of them carry the recessive gene. If only one X chromosome carries it, the normal dominant gene on the other X chromosome suppresses the disease and she remains a carrier. A male has only one X chromosome, so a single recessive gene expresses itself and he shows the disease. This is why haemophilia is uncommon in human females.

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